Written  by:
Laurinda Morris, DVM
Danville Veterinary  Clinic
Danville, Ohio
 

This  week I had the first case in history of raisin toxicity ever seen at  MedVet. My patient was a 56-pound, 5-year-old male neutered lab mix  that ate half a canister of raisins sometime between 7:30 AM and  4:30 PM on Tuesday.  He started with vomiting, diarrhea and  shaking about 1AM on Wednesday but the owner didn't call my  emergency service until 7AM.

I had heard somewhere about  raisins AND grapes causing acute Renal failure but hadn't seen any  formal paper on the
 subject.  We had her bring the dog in immediately. In the meantime, I called  the ER service at MedVet, and the doctor there was like me - had  heard something about it, but .      Anyway,  we contacted the ASPCA National Animal Poison Control Center and they said to give  IV fluids at 1 times maintenance and watch the kidney values for the  next 48-72 hours.

The dog's BUN (blood urea nitrogen level)  was already at 32 (normal less than 27) and creatinine over 5 ( 1.9  is the high end of normal). Both are monitors of kidney function in  the bloodstream. We placed an IV catheter and started the fluids.  Rechecked the renal values at 5 PM and the BUN was over 40 and  creatinine over 7 with no urine production after a liter of fluids.   At the point I felt the dog was in acute renal failure and  sent him on to MedVet for a urinary catheter to monitor urine output  overnight as well as overnight care.

He started vomiting  again overnight at MedVet and his renal values have continued to  increase daily. He produced urine when given lasix as a diuretic. He  was on 3 different anti-vomiting medications and they still couldn't  control his vomiting. Today his urine output decreased again, his  BUN was over 120, his creatinine was at 10, his phosphorus was very  elevated and his blood pressure, which had been staying around 150,  skyrocketed to 220.. He continued to vomit and the owners elected to  euthanize.

This is a very sad case - great dog, great owners  who had no idea raisins could be a toxin. Please alert everyone you  know who has a dog of this very serious  risk.  

Poison  control said as few as 7 raisins or grapes could be toxic. Many  people I know give their dogs grapes or raisins as treats including  our ex-handlers. Any exposure should give rise to immediate  concern.  

Laurinda  Morris, DVM
Danville Veterinary  Clinic
 

TheGroomery@MyGroomerKC.com

Phone 816-444-0313

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